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Updated: Sep 21, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
The diagnosis and treatment of infants with intersex abnormalities
1Harvard Medical School, Massachusetts General Hospital, Boston.
Insights
Pediatric surgical repair requires a multidisciplinary team approach for optimal outcomes in children with complex conditions. Careful attention to surgical techniques and gender assignment factors is crucial for successful anatomic, functional, and psychological results.
Area of Science:
- Pediatric Surgery
- Pediatric Urology
- Pediatric Endocrinology
Background:
- Management of children with complex conditions requires long-term, multidisciplinary care.
- Surgical repair is a critical component of treatment, impacting multiple aspects of a child's life.
Purpose of the Study:
- To highlight the importance of a team approach in managing pediatric surgical cases.
- To emphasize the technical aspects of surgical repairs for optimal patient outcomes.
- To discuss factors influencing gender assignment and surgical timing.
Main Methods:
- Focus on the technical aspects of surgical repairs.
- Consideration of gender assignment criteria.
- Evaluation of factors affecting surgical choice and timing.
Main Results:
- Successful anatomic, functional, and psychological outcomes depend on meticulous surgical technique.
- Multidisciplinary collaboration is essential for comprehensive patient management.
- Informed decisions regarding gender assignment and surgical timing are critical.
Conclusions:
- A team approach involving pediatric surgeons, urologists, and endocrinologists is vital.
- Technical precision in surgical repair is paramount for achieving positive patient outcomes.
- Careful consideration of gender assignment and surgical timing optimizes results for these complex pediatric patients.
Abstract:
Management of these children, which begins in the newborn period and often extends throughout adolescence, should be done as a team approach with pediatric surgeons/urologists and pediatric endocrinologists. Careful attention must be paid to the technical aspects of these repair to ensure successful anatomic, functional, and psychological outcome for these often difficult patients. Although this article concentrates on the technical aspects of the surgical repairs of these children, careful consideration is given to the circumstances dictating gender assignment and the factors that affect the choice and timing of operation.
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