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Pericardial Fluid Exosomes: A New Material to Treat Cardiovascular Disease

Susmita Sahoo1, Prabhu Mathiyalagan1, Roger J Hajjar1

  • 1Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|February 21, 2017
PubMed
Abstract

No abstract available in PubMed .

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Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
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The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
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