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Aloe Vera for Tissue Engineering Applications.

Shekh Rahman1, Princeton Carter2, Narayan Bhattarai3

  • 1Department of Chemical, Biological and Bioengineering, North Carolina A&T State University, Greensboro, NC 27411, USA. srahman@aggies.ncat.edu.

Journal of Functional Biomaterials
|February 21, 2017
PubMed
Summary

Aloe vera (Aloe barbadensis Miller) shows promise in tissue engineering due to its biocompatibility and bioactive components. This review explores its use in scaffolds, gels, and nanofibers for enhanced tissue regeneration.

Keywords:
aloe verabiomaterialsnanofibersregenerative medicinetissue engineering

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Plant-based Therapeutics

Background:

  • Aloe vera (Aloe barbadensis Miller) is a succulent plant with a long history of use in biomedical, pharmaceutical, and cosmetic applications.
  • Recent advancements highlight its potential in tissue engineering, attributed to its biodegradability, biocompatibility, and low toxicity.
  • The plant possesses numerous bioactive components with demonstrated antibacterial, anti-inflammatory, antioxidant, and immune-modulatory effects.

Purpose of the Study:

  • To review the current state of aloe vera in tissue engineering.
  • To discuss the plant's bioactive components, extraction, and processing methods.
  • To explore the prospects of aloe vera in various tissue engineering applications.

Main Methods:

  • Literature review focusing on aloe vera's properties and applications in tissue engineering.
  • Analysis of studies detailing the extraction and processing of aloe vera's bioactive components.
  • Examination of research on aloe vera-based scaffolds, gels, and films, with emphasis on electrospun nanofibers.

Main Results:

  • Aloe vera exhibits favorable characteristics for tissue engineering, including biodegradability and biocompatibility.
  • Its bioactive components actively promote tissue regeneration and growth through various biological mechanisms.
  • Successful applications include its use in scaffolds, gels, and films, particularly in electrospun nanofiber formats.

Conclusions:

  • Aloe vera presents a promising natural resource for developing advanced tissue engineering materials.
  • Its inherent biological activities and material properties support its role in promoting tissue repair and regeneration.
  • Further research into aloe vera-based biomaterials, especially nanofibers, could lead to significant clinical advancements.