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Updated: Mar 7, 2026

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
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Optimization of Bicyclic Lactam Derivatives as NMDA Receptor Antagonists

Margarida Espadinha1, Jorge Dourado1, Rocio Lajarin-Cuesta2,3

  • 1Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.

Chemmedchem
|February 21, 2017
PubMed

Keywords:
NMDA receptorsantagonistsasymmetric synthesisbicyclic lactamsnitrogen heterocycles

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