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Integrating Pharmacoproteomics into Early-Phase Clinical Development: State-of-the-Art, Challenges, and

Savita Nandal1, Tal Burt2

  • 1Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, NJ 07936, USA. savita.nandal@novartis.com.

International Journal of Molecular Sciences
|February 21, 2017
PubMed

Keywords:
Omicsbiomarkerclinical developmentclinical researchdrug developmentdrug toxicityearly phase developmentfirst-in-human (FIH) studiespharmacodynamics (PD)pharmacogenomicspharmacokinetics (PK)pharmacometabolomicsphase 0phase 1phase 2proof-of-conceptproof-of-mechanismproof-of-principleproteomeproteomics

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