Aryne multifunctionalization with benzdiyne and benztriyne equivalents
Jiarong Shi1, Yuanyuan Li1, Yang Li1
1School of Chemistry and Chemical Engineering, Chongqing University, 174 Shazheng Street, Chongqing, 400030, P. R. China. y.li@cqu.edu.cn.
Chemical Society Reviews
|February 21, 2017
Summary
Aryne chemistry enables simultaneous functionalization of adjacent benzene ring positions. Multiaryne equivalents further allow functionalization of all ring positions, creating complex polycyclic aromatic frameworks.
Area of Science:
- Organic Chemistry
- Synthetic Chemistry
Background:
- Aryne chemistry offers unique synthetic capabilities.
- Simultaneous functionalization of vicinal positions on a benzene ring is a key feature.
Purpose of the Study:
- To review the applications of benzdiyne and benztriyne equivalents.
- To highlight their use in synthetic organic chemistry and polycyclic aromatic framework preparation.
Main Methods:
- Focuses on the synthetic utility of aryne chemistry.
- Discusses the application of multiaryne equivalents.
Main Results:
- Benzdiyne and benztriyne equivalents facilitate diverse functionalization patterns.
- Enables the synthesis of complex polycyclic aromatic structures.
Conclusions:
- Aryne chemistry, particularly using multiaryne equivalents, provides powerful tools for constructing intricate molecular architectures.
- This review consolidates knowledge on benzdiyne and benztriyne applications for synthetic chemists.
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