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No blank slates: Pre-existing schemas about pharmaceuticals predict memory for side effects
Monika K Heller1, Sarah C E Chapman1, Rob Horne1
1a Research Department of Practice and Policy , University College London School of Pharmacy , London , UK.
People who believe medicines are more harmful recall fewer side effects and are more likely to attribute unrelated symptoms like headaches as medication side effects. Memory plays a role in this attribution process.
Area of Science:
- Psychology
- Cognitive Science
- Health Psychology
Background:
- Patient beliefs about medications, known as pharmaceutical schemas, influence symptom attribution.
- Perceptions of personal sensitivity also shape these beliefs.
Purpose of the Study:
- To investigate the association between pharmaceutical schemas and memory for medication side effects.
- To determine if memory for side effects mediates the attribution of unrelated symptoms as side effects.
Main Methods:
- An analogue study design was employed.
- Participants reviewed a fictitious asthma drug's patient leaflet listing eight side effects.
- Recall and recognition memory for side effects were measured, alongside attribution of an unlisted symptom (headache) via vignette.
Main Results:
- Beliefs of greater pharmaceutical harm correlated with poorer recall of correct side effects (r=-.273).
- Higher perceived harm also linked to reduced ability to distinguish listed from unlisted side effects (r=-.256).
- Participants perceiving pharmaceuticals as more harmful were more likely to attribute headache as a side effect (r=.381), with recall partially mediating this effect.
Conclusions:
- Pharmaceutical schemas are linked to how well individuals remember side effect information.
- Memory for side effects appears to partially explain why negative beliefs about pharmaceuticals lead to attributing unrelated symptoms as side effects.
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