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[ICD in elderly patients]
1Klinik für Innere Medizin - Kardiologie, Diabetologie & Nephrologie, Evangelisches Krankenhaus Bielefeld, Burgsteig 13, 33617, Bielefeld, Deutschland. Carsten.Israel@evkb.de.
Insights
Implantable cardioverter-defibrillator (ICD) therapy improves prognosis, not symptoms. Decisions for elderly patients require individual assessment of life expectancy, quality of life, and patient preferences.
Area of Science:
- Cardiology
- Medical Ethics
Background:
- Implantable cardioverter-defibrillators (ICDs) offer prognostic benefits but not symptomatic relief.
- Patient selection for ICD implantation requires careful consideration of life expectancy and quality of life.
Purpose of the Study:
- To evaluate the prognostic benefit and safety of ICD therapy in elderly patients.
- To provide guidance on individualizing ICD implantation decisions in older adults.
Main Methods:
- Review of existing data on ICD use in elderly populations.
- Analysis of factors influencing prognostic benefit, including age, comorbidity, and patient preferences.
Main Results:
- Elderly patients experience similar rates of appropriate ICD therapy compared to younger patients.
- Complication rates for ICD implantation and lead longevity are not higher in the elderly.
- Prognostic benefit in primary prevention is less clear in the elderly due to higher competing mortality.
Conclusions:
- ICD indication in elderly patients should be individualized, considering life expectancy, comorbidity, biological age, and patient preferences.
- Age alone should not be a barrier to ICD implantation; complications are not more frequent.
- Deactivation of shock therapy should be discussed with elderly patients nearing end-of-life.
Abstract:
Treatment with an implantable cardioverter-defibrillator (ICD) represents a prognostic but not symptomatic therapy. It should therefore be restricted to patients where an improvement of prognosis is possible and reasonable. ICD implantation should only be performed in patients with a life expectancy of at least 1 year at reasonable quality of life. The decision in which patient improvement of prognosis is no longer a desirable target is problematic, both medically and ethically. It is not entirely clear in which elderly patient an ICD therapy can convey prognostic benefit despite comorbidity and competitive life-threatening diseases, as it is unclear how old age should be defined. In primary prophylaxis of sudden cardiac death, data on a prognostic benefit of the ICD in elderly patients are less clear than in secondary prophylaxis since short-term mortality due to other causes is higher in the elderly. However, elderly ICD patients have a similar rate of appropriate ICD therapy as younger patients. Complications at ICD implantation or long-term lead failure do not occur more frequently in elderly patients and therefore do not represent a reason to withhold ICD implantation in elderly patients or to set an age limit above which ICD implantation should no longer be performed. The ICD indication in elderly patients should be individualized depending on remaining life expectancy, comorbidity, "biological age" and patient preferences which play a particularly important role in elderly patients. Aspects of a potential improvement in quality of life by the ICD which may also serve as a system for antibradycardiac or resynchronization treatment should be included into considerations. Deactivation of at least shock therapy should be discussed in elderly patients fitted with an ICD if the subject is brought up by the patient or if clinical deterioration suggests the need to talk about a "do not resuscitate" order. This talk should be performed before death is imminent and before an electrical storm in terminal illness leads to multiple shocks by the active device.
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