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Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice
Published on: October 17, 2018
ZIKA-RELATED MACULOPATHY
Chee Wai Wong1,2, Si Rui Ng1,2, Chui Ming Gemmy Cheung1,2,3
1Singapore National Eye Centre, Medical Retina Department, Singapore, Singapore.
Purpose:
To report a case of unilateral maculopathy associated with acute Zika virus infection.
Methods:
Observational case report of one patient.
Results:
A 22-year-old man presented with acute blurring of vision 10 days after symptoms of Zika virus infection. Findings resembling unilateral acute idiopathic maculopathy of the right eye were noted on ophthalmoscopy, fluorescein angiography, indocyanine green angiography, and optical coherence tomography. Localized macular dysfunction in the right eye was noted on multifocal electroretinography. The left eye was normal. He was managed conservatively with resolution of symptoms in 3 weeks.
Conclusion:
We describe a case of unilateral acute idiopathic maculopathy-like disease in a patient with reverse transcriptase polymerase chain reaction-confirmed Zika virus infection.
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