Related Experiment Video
Updated: Mar 7, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022
Sustained Resolution of Macular Retinoschisis After Trabeculectomy in a Patient With Progressive Glaucoma
Rany Woo1, Handan Akil, Nicole Koulisis
1*Department of Ophthalmology, David Geffen School of Medicine, Jules Stein Eye Institute †Department of Ophthalmology, David Geffen School of Medicine, Doheny Eye Institute, UCLA, Los Angeles, CA ‡University of Massachusetts Medical School, Worcester, MA §Department of Ophthalmology, Eye Institute, University of Washington School of Medicine, Seattle, WA.
Purpose:
To evaluate the clinical characteristics of a patient with primary open-angle glaucoma in whom macular retinoschisis resolved completely after trabeculectomy consistently lowered intraocular pressure (IOP).
Methods:
A single case report.
Results:
We report a case of retinoschisis involving the macula in a patient with primary open-angle glaucoma in the absence of myopic maculopathy, optic nerve anomaly, or x-linked retinoschisis. The patient's glaucoma was associated with progressive visual field loss in the setting of IOP fluctuations related to posture. A trabeculectomy reduced IOP and posture-related IOP fluctuations with subsequent resolution of macular retinoschisis. In the 1-year postoperative period following trabeculectomy, the patient has remained without retinoschisis and visual fields have been stable.
Conclusions:
Improved IOP control resulting in resolution of retinoschisis may distinguish retinoschisis associated with glaucoma from other forms of retinoschisis.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment

