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Related Concept Videos

Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Reticular Dermis01:15

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Accessory Structures of the Skin: Sebaceous Glands01:21

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Desmosomes01:05

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The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein...
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Papillary Dermis01:11

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: Mar 7, 2026

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin
05:21

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin

Published on: July 3, 2025

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Demodicidosis Involving Human Face.

A K Hati, Neelam Tandon, S K Bhattacharya

    Indian Journal of Dermatology, Venereology and Leprology
    |February 23, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Follicle mites, Demodex folliculorum, were found in patients with rosacea-like lesions. Treatment with lindane lotion effectively improved all patients' conditions, suggesting a link between mites and the skin condition.

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    Granulocyte-dependent Autoantibody-induced Skin Blistering
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    Area of Science:

    • Dermatology
    • Parasitology
    • Microbiology

    Background:

    • Rosacea-like lesions can be associated with microscopic Demodex mites.
    • Demodex folliculorum (DF) is a common mite found on human skin.

    Purpose of the Study:

    • To investigate the presence of Demodex folliculorum in patients with rosacea-like lesions.
    • To evaluate the efficacy of lindane treatment for these conditions.

    Main Methods:

    • Microscopic examination of facial skin samples from 9 patients with rosacea-like lesions.
    • Comparison with control cases where mites were absent.
    • Topical application of 1% lindane lotion for seven consecutive days.

    Main Results:

    • Demodex folliculorum mites were identified in varying numbers on the affected skin of all 9 patients.
    • No mites were found in the control group.
    • All patients showed clinical improvement after lindane treatment.

    Conclusions:

    • Demodex folliculorum infestation is strongly associated with rosacea-like facial lesions.
    • Topical lindane is an effective treatment for Demodex-associated rosacea-like conditions.