Psoriasis - a Clinical and Some Biochemical Investigative Study

Area of Science:

• Dermatology
• Clinical Medicine

Background:

• Psoriasis is a chronic inflammatory skin condition with varying clinical presentations.
• Understanding the epidemiological and biochemical profiles of psoriasis patients is crucial for effective management.

Purpose of the Study:

• To analyze the demographic characteristics of psoriasis patients.
• To investigate the prevalence of specific clinical manifestations and biochemical abnormalities in psoriasis.

Main Methods:

• A retrospective study of 132 psoriasis cases at Medical College Hospital, Rohtak.
• Data collection included patient demographics, clinical lesion sites, family history, and biochemical parameters.

Main Results:

• Psoriasis accounted for 0.8% of hospital patients, with 122 cases aged 11-40 years.
• A male to female ratio of 4:1 was observed. Facial lesions occurred in 12 patients, and mucous membrane involvement in 7.
• Biochemical findings included hypercalcemia (10%), hypocalcemia (15%), elevated serum magnesium (40%), and elevated serum uric acid (26.6%).

Conclusions:

• Psoriasis predominantly affects young adults, with a higher incidence in males.
• Biochemical abnormalities such as hypermagnesemia and hyperuricemia are common in psoriasis patients, warranting further investigation.