Comparative Investigation with Fluprednylidene Acetate (decoderma)

The therapeutic efficacy of a new fluorinated steriod, 0. 1% fluprednylidene -21 acetate (Decoderm) cream was compared to betamethasone and triamcinolone in two double blind clinical trials. All the three topical steroids were effective in various steroid responsive dermatoses within one week and the beneficial effects continued throughout the four weeks of the trials. The various signs and symptoms, such as erythema, pruritus, oedema, exudation, scaling, vesicles, crusting, lichenification and burning, improved significantly with each of the steroid under trial. Fluprednylindine-21 acetate (Decoderm) cream represents an important addition to the present,y available topical steroids.