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Functional Characterization of Na+/H+ Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane
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SLC2A3 single-nucleotide polymorphism and duplication influence cognitive processing and population-specific risk for

Sören Merker1, Andreas Reif2, Georg C Ziegler1

  • 1Division of Molecular Psychiatry, ADHD Clinical Research Unit, Laboratory of Translational Neuroscience, Center of Mental Health, University of Würzburg, Würzburg, Germany.

Journal of Child Psychology and Psychiatry, and Allied Disciplines
|February 23, 2017
PubMed
Summary

Genetic variations in SLC2A3, impacting glucose transporter-3 (GLUT3) function, are linked to attention-deficit/hyperactivity disorder (ADHD). This research provides evidence for GLUT3 dysfunction contributing to ADHD

Keywords:
SLC2A3Attention-deficit/hyperactivity disordercopy number variantsduplicationenergy homeostasisfrontostriatal networkglucose transportersingle-nucleotide polymorphisms

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