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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
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Articles linked to this work by shared authors, journal, and citation graph.

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Geriatrie et psychologie neuropsychiatrie du vieillissement·2022
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Satisfaction and difficulties of French professional home caregivers in supporting older people with Alzheimer's disease or alcohol misuse.

Health & social care in the community·2017
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[Old age and smoking].

Soins. Gerontologie·2017
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Caregivers' representations of elders who drink too much alcohol: crossroads between professional home caregivers and hospitals nurses.

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[Not Available].

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Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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[Elderly women and alcohol].

Alba Moscato1

  • 1Laboratoire de psychopathologie et processus de santé, Institut universitaire, Paris-Descartes-Sorbonne Paris-Cité, 71 avenue Edouard-Vaillant, 92774 Boulogne-Billancourt cedex, France.

Soins. Gerontologie
|February 23, 2017
PubMed
Summary
This summary is machine-generated.

Alcohol abuse in elderly women may stem from psychological suffering and serve as a coping mechanism during aging. Addressing their mental health needs is crucial for effective support and adjustment.

Keywords:
adjustmentaetiological hypothesesageingajustementalcoholalcoolfemmehypothèses étiologiquesvieillissementwoman

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Area of Science:

  • Gerontology
  • Psychiatry
  • Sociology

Background:

  • Alcohol abuse is a significant issue among the elderly, particularly women.
  • Understanding the underlying psychological factors is essential for effective intervention.
  • Aging presents unique challenges that can contribute to substance misuse.

Purpose of the Study:

  • To explore the reasons behind alcohol abuse in elderly women.
  • To examine psychological suffering as a potential cause.
  • To highlight the importance of mental health support for this demographic.

Main Methods:

  • Qualitative analysis of psychological factors.
  • Exploration of narcissistic retreat theory in aging.
  • Review of existing literature on elderly women's mental health and alcohol use.

Main Results:

  • Psychological suffering is a key factor in alcohol abuse among elderly women.
  • Alcohol consumption may function as a narcissistic retreat during the aging process.
  • The need for tailored mental health interventions is evident.

Conclusions:

  • Addressing the psychological well-being of elderly women is critical for managing alcohol abuse.
  • Supportive and understanding approaches are necessary to help them navigate aging.
  • Mental health services should be accessible and responsive to the needs of aging women.