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Listeria monocytogenes-induced endogenous endophthalmitis in an otherwise healthy

C P Lohmann1, V P Gabel, M Heep

  • 1University Eye Clinic, Regensburg.

European Journal of Ophthalmology
|February 23, 2017
PubMed

Insights

Early polymerase chain reaction (PCR) identification of Listeria monocytogenes in endogenous endophthalmitis cases can lead to complete visual recovery. Prompt diagnosis and treatment are crucial for better outcomes in this rare infection.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Listeria monocytogenes is an uncommon cause of endogenous endophthalmitis.
  • Fifteen cases have been documented, typically presenting with severe visual loss due to diagnostic delays.

Purpose of the Study:

  • To report a case of endogenous endophthalmitis caused by Listeria monocytogenes.
  • To highlight the utility of early pathogen identification and prompt treatment for visual recovery.

Main Methods:

  • A case study of a 73-year-old male with acute iridocyclitis and secondary glaucoma.
  • Diagnosis involved anterior chamber paracentesis for polymerase chain reaction (PCR) analysis.
  • Treatment included systemic antibiotic therapy.

Main Results:

  • Polymerase chain reaction (PCR) enabled rapid identification of Listeria monocytogenes in aqueous humor.
  • Early diagnosis and targeted antibiotic treatment led to complete recovery of visual acuity.
  • This contrasts with typical cases of delayed diagnosis and profound visual loss.

Conclusions:

  • Polymerase chain reaction (PCR) is a highly effective tool for diagnosing intraocular infections.
  • Early and accurate pathogen identification is critical for successful management of endogenous endophthalmitis.

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