Related Experiment Video
Updated: Mar 7, 2026

Microfluidic Dry-spinning and Characterization of Regenerated Silk Fibroin Fibers
Published on: September 4, 2017
Production of High Performance Bioinspired Silk Fibers by Straining Flow Spinning
Rodrigo Madurga1,2, Alfonso M Gañán-Calvo3, Gustavo R Plaza1,2
1Centro de Tecnología Biomédica, Universidad Politécnica de Madrid , 28223 Pozuelo de Alarcón (Madrid), Spain.
Abstract:
In the last years, there has been an increasing interest in bioinspired approaches for different applications, including the spinning of high performance silk fibers. Bioinspired spinning is based on the natural spinning system of spiders and worms and requires combining changes in the chemical environment of the proteins with the application of mechanical stresses. Here we present the novel straining flow spinning (SFS) process and prove its ability to produce high performance fibers under mild, environmentally friendly conditions, from aqueous protein dopes. SFS is shown to be an extremely versatile technique which allows controlling a large number of processing parameters. This ample set of parameters allows fine-tuning the microstructure and mechanical behavior of the fibers, which opens the possibility of adapting the fibers to their intended uses.

