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Related Concept Videos

Obesity01:24

Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Psychoneuroimmunology: Diabetes and Cancer01:19

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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

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Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
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Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

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Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
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Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Drug Dosing: Obese Patients01:21

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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Author Spotlight: Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis
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Psoriasis and Obesity.

Peter Jensen1, Lone Skov

  • 1Department of Dermatology and Allergy, Herlev and Gentofte Hospital, Hellerup, Denmark.

Dermatology (Basel, Switzerland)
|February 23, 2017
PubMed
Summary
This summary is machine-generated.

Obesity is linked to psoriasis development and severity. Weight reduction may improve psoriasis outcomes, highlighting the importance of weight management for patients with this chronic inflammatory skin condition.

Keywords:
Nutritional careObesityPsoriasis

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Area of Science:

  • Dermatology
  • Immunology
  • Public Health

Background:

  • Psoriasis is a chronic inflammatory skin disease with multifactorial etiology.
  • Obesity is a prevalent comorbidity associated with psoriasis.
  • Obesity may influence psoriasis incidence, severity, and treatment efficacy.

Purpose of the Study:

  • To review the current literature on the association between obesity and psoriasis.
  • To explore the role of obesity as a risk factor and exacerbating factor in psoriasis.
  • To discuss the implications of weight management in psoriasis care.

Main Methods:

  • Literature review of studies investigating obesity and psoriasis.
  • Analysis of evidence linking excess body weight to psoriasis development and progression.
  • Examination of the impact of weight reduction on psoriasis severity.

Main Results:

  • Obesity is identified as a risk factor for developing psoriasis.
  • Excess body weight can worsen existing psoriasis.
  • Weight reduction interventions show potential for improving psoriasis severity in overweight individuals.

Conclusions:

  • A significant association exists between obesity and psoriasis.
  • Effective weight control is crucial for managing psoriasis and its comorbidities.
  • Further research into weight management strategies for psoriasis patients is warranted.