Abscess caused by Salmonella enteritidis within a glioblastoma multiforme

Area of Science:

• Neuroscience
• Infectious Diseases
• Oncology

Background:

• Focal intracranial infections are rare, particularly those caused by Salmonella species.
• Glioblastoma multiforme is an aggressive primary brain tumor.
• Salmonella infections typically manifest as gastroenteritis.

Observation:

• A rare case of focal intracranial infection was identified.
• The infection was localized within a glioblastoma multiforme tumor.
• The causative agent was identified as Salmonella enteritidis.

Findings:

• A brain abscess was diagnosed in a patient with glioblastoma multiforme.
• Cerebral abscess was attributed to Salmonella enteritidis.
• This represents an unusual presentation of Salmonella infection.

Implications:

• This case expands the known spectrum of Salmonella-related central nervous system infections.
• Highlights the importance of considering Salmonella in the differential diagnosis of brain abscesses, especially in immunocompromised patients or those with underlying malignancies.
• Suggests potential mechanisms for Salmonella translocation to the central nervous system in the context of brain tumors.