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Updated: Mar 7, 2026
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Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets
Published on: February 2, 2024
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Abstract:
Decreased activity of the chromatin remodeling factor gene SMARCB1 drives a switch in pancreatic cancer cells toward a more aggressive, mesenchymal state. This change makes the tumors more susceptible to drugs that target protein metabolism and associated stress responses.
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