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IgG4-related disease in an adolescent with radiologic-pathologic correlation
Renato Cesar Ferreira da Silva1, Scott M Lieberman2, Henry T Hoffman3
1Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA.
Immunoglobulin G4-related disease (IgG4RD) can affect children, presenting as submandibular gland swelling. Early recognition by radiologists is crucial for accurate diagnosis in pediatric cases.
Area of Science:
- Immunology
- Pathology
- Radiology
Background:
- Immunoglobulin G4-related disease (IgG4RD) is a rare immune-mediated fibroinflammatory condition.
- While typically affecting adults, IgG4RD can occur in pediatric patients, often with nonspecific symptoms.
- Isolated submandibular gland involvement is exceptionally rare in children.
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