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Published on: September 6, 2017
The use and yield of continuous EEG in critically ill patients: A comparative study of three centers
Vincent Alvarez1, Andres A Rodriguez Ruiz2, Suzette LaRoche3
1Department of Neurology, Hôpital du Valais, Sion, Switzerland; Department of Clinical Neurosciences, CHUV and University of Lausanne, Lausanne, Switzerland; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Objective:
Continuous EEG (cEEG) monitoring of critically ill patients has gained widespread use, but there is substantial reported variability in its use. We analyzed cEEG and antiseizure drug (ASD) usage at three high volume centers.
Methods:
We utilized a multicenter cEEG database used daily as a clinical reporting tool in three tertiary care sites (Emory Hospital, Brigham and Women's Hospital and Yale - New Haven Hospital). We compared the cEEG usage patterns, seizure frequency, detection of rhythmic/periodic patterns (RPP), and ASD use between the sites.
Results:
5792 cEEG sessions were analyzed. Indication for cEEG monitoring and recording duration were similar between the sites. Seizures detection rate was nearly identical between the three sites, ranging between 12.3% and 13.6%. Median time to first seizure and detection rate of RPPs were similar. There were significant differences in doses of levetiracetam, valproic acid, and lacosamide used between the three sites.
Conclusions:
There was remarkable uniformity in seizure detection rates within three high volume centers. In contrast, dose of ASD used frequently differed between the three sites.
Significance:
These large volume data are in line with recent guidelines regarding cEEG use. Difference in ASD use suggests discrepancies in how cEEG results influence patient management.
