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Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
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Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

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Ceftaroline-Resistant, Daptomycin-Tolerant, and Heterogeneous Vancomycin-Intermediate Methicillin-Resistant

Masayuki Nigo1, Lorena Diaz2,3, Lina P Carvajal2

  • 1Department of Internal Medicine, Division of Infectious Diseases, University of Texas Medical School at Houston, Houston, Texas, USA.

Antimicrobial Agents and Chemotherapy
|February 25, 2017
PubMed

Insights

This study details a difficult-to-treat case of methicillin-resistant Staphylococcus aureus (MRSA) infective endocarditis. The MRSA strain exhibited resistance to ceftaroline and tolerance to daptomycin, complicating patient treatment.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Infective endocarditis (IE) poses significant treatment challenges, particularly when caused by multidrug-resistant pathogens.
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of IE, and emerging resistance patterns complicate therapeutic options.
Keywords:
Staphylococcus aureusceftarolineendocarditis

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