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Heart failure complicating with SAPHO syndrome.
Takeshi Nishimura1, Shota Kikuta1, Satoshi Ishihara1
1Hyogo-ken Saigai Iryo Center, Kobe, Japan.
BMJ Case Reports
|February 25, 2017
Summary
A case study suggests a potential link between SAPHO syndrome and acute heart failure. This rare condition, characterized by inflammatory symptoms, may contribute to cardiac complications, warranting further investigation into the underlying mechanisms.
Area of Science:
- Rheumatology
- Cardiology
- Dermatology
Background:
- SAPHO syndrome is a rare autoinflammatory disorder characterized by synovitis, acne, pustulosis, hyperostosis, and osteomyelitis.
- Acute heart failure is a sudden, life-threatening condition requiring prompt medical attention.
Observation:
- A 65-year-old male presented with acute heart failure, clavicular swelling, and pustulosis on soles.
- Physical examination and symptoms were consistent with SAPHO syndrome criteria.
Findings:
- The patient's condition rapidly improved with antihypertensive medication and non-invasive ventilation.
- A potential association between SAPHO syndrome and acute heart failure was suspected.
Implications:
- This case highlights a possible, yet unclarified, etiological link between SAPHO syndrome and heart failure.
- Further research is necessary to elucidate the relationship and underlying pathophysiology.
- Understanding this connection may improve diagnostic and therapeutic strategies for patients with overlapping conditions.
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