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Updated: Mar 7, 2026

In Utero Intra-cardiac Tomato-lectin Injections on Mouse Embryos to Gauge Renal Blood Flow
Published on: February 4, 2015
Plasticity of Renin Cells in the Kidney Vasculature
R Ariel Gomez1, Maria Luisa S Sequeira Lopez2
1University of Virginia School of Medicine, Child Health Research Center, 409 Lane Road, MR4 Building Room 2001, Charlottesville, VA, 22908, USA. rg@virginia.edu.
Abstract:
During development, renin cells are precursors for arteriolar smooth muscle, mesangial cells, and interstitial pericytes. Those seemingly differentiated descendants retain the memory to re-express renin when there is a threat to homeostasis. Understanding how such molecular memory is constructed and regulated would be crucial to comprehend cell identity which is, in turn, intimately linked to homeostasis.
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