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Polylactide-caprolactone composite mesh for ventral hernia repair: a prospective, randomized, single-blind controlled
Ying-Mo Shen1, Qi Li1, Jie Chen2
1Department of Hernia and Abdominal Wall Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Minerva Chirurgica
|February 25, 2017
Summary
The new EasyProsthes™ mesh (EPM) shows similar safety and effectiveness compared to Parietex™ Composite (PCO) for laparoscopic ventral hernia repair. This study found comparable rates of complications like seroma and adhesions between the two composite meshes.
Area of Science:
- Minimally Invasive Surgery
- Biomaterials Science
- Surgical Oncology
Background:
- Composite surgical meshes are prevalent in laparoscopic ventral hernia repair.
- High rates of postoperative complications are associated with current mesh types.
- A novel composite polypropylene mesh coated with poly L-lactide-co-ε-caprolactone (EasyProsthes™) was developed.
Purpose of the Study:
- To evaluate the safety and effectiveness of EasyProsthes™ mesh (EPM) in laparoscopic ventral hernia repair.
- To compare EPM with Parietex™ Composite (PCO) regarding postoperative complications.
- To assess outcomes including hernia recurrence, chronic pain, seroma, fistula, obstruction, infection, and adhesions.
Main Methods:
- A randomized, controlled trial involving 80 patients undergoing laparoscopic ventral hernia repair.
- Patients were divided into two groups: EPM (N.=40) and PCO (N.=40).
- Outcomes were evaluated over a 12-month follow-up period.
Main Results:
- No significant differences were observed in mesh-viscera adhesions (2.5% EPM vs. 5% PCO) or postoperative wound infections (1 patient each group).
- Incidence of seroma formation was comparable (42.5% EPM vs. 52.2% PCO).
- No cases of intestinal fistulas, obstruction, abdominal infections, chronic pain, or hernia recurrence were reported.
Conclusions:
- EasyProsthes™ mesh (EPM) demonstrates comparable safety and effectiveness to Parietex™ Composite (PCO) in laparoscopic ventral hernia repair.
- The incidence of postoperative complications was similar between the EPM and PCO groups.
- EPM is a safe and effective option for ventral hernia repair surgeries.
