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Updated: Aug 18, 2026

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)
Published on: August 21, 2016
Identification of an LtB4-protein complex as evidence of endothelial cell cytotoxic activity (ECA) in progressive
H R Deicher1, F Drenk, G Hoffman
1Abt. Immunologie und Transfusionsmedizin, Medizinische Hochschule Hannover, FRG.
Abstract:
A low molecular weight LtB4-carrier complex has been identified as endothelial cytotoxic activity (ECA) in progressive systemic sclerosis (PSS) patients' sera. ECA is thought to play a key role in the initiation of obliterative vasculopathy, a basic tissue lesion of this disease.
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