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Updated: Mar 7, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
Published on: July 8, 2025
Are psychogenic non-epileptic seizures just another symptom of conversion disorder?
Richard A A Kanaan1,2, Roderick Duncan3, Laura H Goldstein2
1Department of Psychiatry, Austin Health, University of Melbourne, Heidelberg, Victoria, Australia richard.kanaan@unimelb.edu.au.
Background:
Psychogenic non-epileptic seizures (PNES) are classified with other functional neurological symptoms as 'Conversion Disorder', but there are reasons to wonder whether this symptomatology constitutes a distinct entity.
Methods:
We reviewed the literature comparing PNES with other functional neurological symptoms.
Results:
We find eight studies that directly examined this question. Though all but one found significant differences-notably in presenting age, trauma history, and dissociation-they were divided on whether these differences represented an important distinction.
Conclusion:
We argue that the aetiological and mechanistic distinctions they support, particularly when bolstered by additional data, give reason to sustain a separation between these conditions.
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