Related Experiment Video
Updated: Mar 7, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Air pollution and ST-elevation myocardial infarction treated with primary percutaneous coronary angioplasty: A direct
Marco Zuin1, Gianluca Rigatelli2, Fabio dell'Avvocata2
1Division of Cardiology, Rovigo General Hospital, Rovigo, Italy; Section of Internal and Cardiopulmonary Medicine, Department of Medical Science, University of Ferrara, Ferrara, Italy.
Insights
Higher levels of air pollutants like nitrogen dioxide (NO2), particulate matter (PM10), and ozone (O3) correlate with increased hospital admissions for ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). This study highlights a significant link between daily air quality and acute cardiac events.
Area of Science:
- Environmental Health
- Cardiology
- Public Health
Background:
- Air pollution is a growing concern for public health.
- The impact of specific air pollutants on acute cardiovascular events like ST-elevation myocardial infarction (STEMI) requires further investigation.
- Primary percutaneous coronary intervention (PCI) is a critical treatment for STEMI.
Purpose of the Study:
- To assess the relationship between daily air pollutant concentrations and hospital admissions for primary PCI in STEMI patients.
- To investigate the correlation between atmospheric pressure and STEMI admissions.
- To determine if air pollutant levels exceeding safety thresholds are associated with increased STEMI incidence.
Main Methods:
- Retrospective analysis of medical and instrumental data from January 2012 to March 2016.
- Inclusion of patients admitted with STEMI and treated with primary PCI.
- Collection of daily atmospheric pressure and air pollutant data (NO2, PM10, O3, SO2, CO) from a regional meteorological service.
Main Results:
- STEMI patients treated with primary PCI were more frequent with atmospheric pressure > 1013.15 hPa (61.8%).
- High incidences of STEMI admissions occurred when NO2 (83.1%), PM10 (52%), and O3 (8.5%) exceeded safety thresholds.
- Significant positive correlations were observed between daily STEMI admissions and daily levels of NO2 (r=0.205), PM10 (r=0.349), and O3 (r=0.191).
Conclusions:
- A direct and significant correlation exists between daily STEMI admissions and daily concentrations of NO2, PM10, and O3.
- Elevated levels of these air pollutants may contribute to an increased incidence of STEMI requiring primary PCI.
- Findings underscore the importance of air quality monitoring in cardiovascular health management.
Purpose:
The relationships between air pollutant concentration levels and admission for primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) have never been assessed.
Methods:
We retrospectively reviewed 4 consecutive years of medical and instrumental data (1st January 2012 to 1st March 2016) to identify patients admitted with STEMI and subsequently treated with primary PCI in our third referral center. Daily atmospheric pressure data (in hectopascal [hPa]) and air pollutant concentration levels were obtained from the regional meteorological service which had a monitoring site in our city (Rovigo, Italy). Pollutants investigated were nitrogen dioxide (NO2), particulate matter ≤10μm (PM10), ozone (O3), sulfur dioxide (SO2) and carbon monoxide (CO). Safety air concentration levels for the air pollutants were also considered.
Results:
PCI in STEMI patients was more frequent when AP was higher than 1013.15hPa (61.8% vs 38.2%, p<0.001). The incidences of STEMI patients when NO2, PM10 and O3 levels overcame the safe threshold were 83.1%, 52% and 8.5%, respectively. A positive correlation was found between the daily number of STEMI subsequently treated with primary PCI and the air pollutant levels of the same day for NO2 (r=0.205, p=0.001), PM10 (r=0.349, p<0.0001) and O3 (r=0.191, p=0.002).
Conclusions:
A direct and significant correlation exists between the number of daily STEMI patients and the NO2, PM10 and O3 air concentration levels of the same day.
More Related Videos
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
06:59Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Coronary Artery Disease V: Interprofessional Care
Angina IV: Management