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Updated: Mar 7, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Human papilloma virus dermatosis in human immunodeficiency virus-positive patients: A 14-year retrospective study in
Almudena Nuno-Gonzalez1, Juan Emilio Losa Garcia2, José Luis López Estebaranz3
1Universidad Rey Juan Carlos, Madrid, España; Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España.
Introduction:
The incidence of the human papilloma virus (HPV) has not dropped in HIV-positive patients despite the discovery of antiretroviral therapy (ART). Our goal is to assess the prevalence of HPV in HIV patients and its relationship with the epidemiological and virological characteristics of HIV patients.
Patients And Methods:
Retrospective cohort of 965 patients diagnosed with HIV from 1998 to 2012. We analyzed patients' demographic factors and factors related to the HPV.
Results:
Of the 965 patients examined, 333 consulted a dermatologist. Of these, 52 patients had genital warts (15.6%), 43 had common warts (12.9%) and 8% had both conditions. In total, 28.5% of patients had a skin lesion caused by HPV.
Discussion And Conclusion:
This is the first longitudinal observational study carried out on HIV-positive patients in the era of ART in which HPV infection is the most common skin pathology. We observed a similar trend in countries with access to ART. This study spreads awareness on the importance of preventing HPV and the difficulty of treating it in HIV-positive patients.
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