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Etretinate modulates the leukotriene B4 induced intra-epidermal accumulation of polymorphonuclear leukocytes
A M Lammers1, P C van de Kerkhof
1Department of Dermatology, University of Nijmegen, The Netherlands.
The British Journal of Dermatology
|September 1, 1987
Abstract:
The effect of etretinate on the intra-epidermal accumulation of polymorphonuclear leukocytes following epicutaneous application of leukotriene B4 was studied in five psoriatic patients. Polymorphonuclear leukocytes were quantified using the marker enzyme elastase. An inverse relationship was found between the dosage of etretinate and the number of infiltrating polymorphonuclear leukocytes.