Related Experiment Video
Updated: Mar 7, 2026

An R-Based Landscape Validation of a Competing Risk Model
Published on: September 16, 2022
Modeling of variability and uncertainty in human health risk assessment
1Dept. of Mathematics, Dibrugarh University, Dibrugarh, 786004, India.
Abstract:
Health risk assessments have been carried out worldwide to examine potential health risk due to exposure to toxic contaminants in various environments. In risk assessment, it is most important to know the nature of all available information, data or model parameters. It is observed that available information/data are tainted with uncertainty and variability in the same time, i.e., uncertainty and variability co-exist. In such situation it is important to devise method for processing both uncertainty and variability into same framework and which is an open issue. In this regards, this paper presents an algorithm to combined approach to propagate variability and uncertainty in the same framework. The differences and advantages of this algorithm over the existing methods are presented below: •The representation of uncertain model parameters are probabilistic together with generalized fuzzy numbers and normal interval valued fuzzy numbers.•The results obtained are then interpreted in terms of p-box and fuzzy numbers.•The advantage of this approach over the existing methods is that this approach gives an accurate resultant fuzzy number which is of trapezoidal type generalized fuzzy number that is different from the existing methods.
Related Concept Videos
Mechanistic Models: Compartment Models in Individual and Population Analysis
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions
Variability: Analysis
The range is a simple measure of variability, indicating the difference between the highest and...
Uncertainty: Confidence Intervals
Uncertainty: Overview

