Related Experiment Video
Updated: Mar 7, 2026

Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
Published on: June 14, 2020
Study of Ulcero-membranous Lesions of Tonsil in an Indian Scenario
D Sridhar Reddy1, A Shoban Babu1, J B S Rathod1
1Department of ENT, Osmania Medical College, Plot No: 138, Mallikarjun Nagar, North GSI-Post, Chintalkunta, L. B. Nagar, Hyderabad, 500 068 India.
'Ulcero-membranous lesions over tonsil' is a special entity, which puzzles every physician and surgeon because of it's diverse etiology. Every insult to the tonsil heals by ulcer and later membrane formation. A retrospective study has been conducted at our institute to analyse the cases of ulcero-membranous lesions of tonsil in terms of etiology, clinical features, diagnosis, treatment protocols and outcome in an Indian context. Diphtheria, if not detected early and treated, can lead to significant morbidity and mortality because of critical complications. Diphtheria mainly affects children aged between 1 and 5 years, however, due to good vaccine coverage, a shift in age incidence has been observed from preschool to school age (5-15 years) with more and more cases now being reported in adults. The health agencies and the government will have to take maximum efforts to increase immunization coverage as India has witnessed the highest number of cases in the world for the year 2015.
'Ulcero-membranous lesions over tonsil' is a special entity, which puzzles every physician and surgeon because of it's diverse etiology. Every insult to the tonsil heals by ulcer and later membrane formation. A retrospective study has been conducted at our institute to analyse the cases of ulcero-membranous lesions of tonsil in terms of etiology, clinical features, diagnosis, treatment protocols and outcome in an Indian context. Diphtheria, if not detected early and treated, can lead to significant morbidity and mortality because of critical complications. Diphtheria mainly affects children aged between 1 and 5 years, however, due to good vaccine coverage, a shift in age incidence has been observed from preschool to school age (5-15 years) with more and more cases now being reported in adults. The health agencies and the government will have to take maximum efforts to increase immunization coverage as India has witnessed the highest number of cases in the world for the year 2015.
Related Concept Videos
Tonsillitis I: Introduction
Etiology
Three primary contributing factors have been identified.
Tonsillitis II: Management
Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:

