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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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Obstructive Sleep Apnea: Women's Perspective.

Shazia Jehan1, Evan Auguste1, Ferdinand Zizi1

  • 1Departments of Population Health, Center for Healthful Behavior Change, Health and Behavior, New York University School of Medicine, USA.

Journal of Sleep Medicine and Disorders
|February 28, 2017
PubMed
Summary
This summary is machine-generated.

Sleep-disordered breathing (SDB) involves airflow limitation and hypoxia, causing disturbed sleep in men and women. Women experience more sleep issues due to hormonal influences and conditions like pregnancy and menopause.

Keywords:
CPAPCVDCardiovascularEstrogenGenderHormonesMelatoninMenopauseOSAObstructive sleep apneaPerimenopausePostmenopausePremenopauseProgesteroneSDBSleep-disordered breathingWomen

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Area of Science:

  • Sleep Medicine
  • Respiratory Medicine
  • Endocrinology

Background:

  • Sleep-disordered breathing (SDB) is characterized by airflow limitation, chronic intermittent hypoxia, or apnea.
  • These SDB events can cause tissue hypoperfusion, recurrent arousals, and inflammation, contributing to disturbed sleep in both sexes.
  • Sleep patterns exhibit sex-based differences throughout the lifespan, potentially influenced by female reproductive hormones.

Purpose of the Study:

  • To explore the influence of female reproductive hormones on sleep patterns and sleep-disordered breathing.
  • To identify factors contributing to SDB in women, considering hormonal fluctuations and associated conditions.

Main Methods:

  • Review of existing literature on sleep-disordered breathing, hormonal influences, and sex differences in sleep.
  • Analysis of factors contributing to SDB in women, including pregnancy and menopause.

Main Results:

  • Women report more sleep complaints compared to men.
  • Female sleep is significantly influenced by gonadotropic hormones, pregnancy, and menopausal changes.
  • Factors such as vasomotor symptoms, hormonal shifts, circadian rhythm disruptions, mood disorders, and lifestyle contribute to SDB in women.

Conclusions:

  • Hormonal factors play a crucial role in the presentation and experience of SDB in women.
  • Understanding these sex-specific influences is vital for diagnosing and managing SDB in the female population.
  • Further research into hormonal modulation of SDB is warranted for targeted therapeutic strategies.