Primary ureteral leiomyosarcoma in a dog
F W Yap1, X B Huizing1, R Rasotto2
1The Centre for Small Animal Studies, Animal Health Trust, Newmarket, UK.
Australian Veterinary Journal
|February 28, 2017
Summary
Ureteral leiomyosarcoma is a rare retroperitoneal mass in dogs causing abdominal pain. Despite surgical removal and chemotherapy, local recurrence led to a poor prognosis in this canine case.
Area of Science:
- Veterinary Oncology
- Canine Pathology
Background:
- Leiomyosarcoma is a rare soft tissue sarcoma.
- Retroperitoneal masses can present with non-specific clinical signs.
Observation:
- A 6-year-old Labrador Retriever presented with acute abdominal pain and lethargy.
- A retroperitoneal mass involving the right ureter was identified, confirmed as leiomyosarcoma.
- The mass recurred locally despite complete surgical excision and adjuvant chemotherapy.
Findings:
- Complete surgical excision of the ureteral leiomyosarcoma was achieved initially.
- Recurrence of leiomyosarcoma at the surgical site occurred within 3 months postoperatively.
- Chemotherapy with doxorubicin and chlorambucil failed to control tumor progression.
Implications:
- Ureteral leiomyosarcoma should be considered in the differential diagnosis of retroperitoneal masses in dogs.
- Local recurrence is a significant challenge in managing canine ureteral leiomyosarcoma.
- This case highlights the poor prognosis associated with recurrent ureteral leiomyosarcoma despite multimodal treatment.
Keywords:
acute abdomencomputed tomographydogsintravenous urographyleiomyosarcomaureteronephrectomyurinary incontinence
