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Clinic-Based Study on Meibomian Gland Dysfunction in Japan
1Department of Ophthalmology, Inouye Eye Hospital, Tokyo, Japan.
Investigative Ophthalmology & Visual Science
|February 28, 2017
Summary
The prevalence of meibomian gland dysfunction (MGD) in Japanese adults over 50 is high, affecting 74.5% of individuals. This finding suggests a greater prevalence of MGD in Tokyo compared to Spanish populations.
Area of Science:
- Ophthalmology
- Public Health
Background:
- Meibomian gland dysfunction (MGD) is a common condition affecting the eyes.
- Previous studies have estimated MGD prevalence in various populations.
Purpose of the Study:
- To estimate the prevalence of meibomian gland dysfunction (MGD) in the Japanese population.
- To compare MGD prevalence in Japan with that of Spanish Caucasians.
Main Methods:
- A clinical study was conducted on 510 patients aged 50+ undergoing cataract surgery.
- Diagnostic criteria for MGD included secretion quality, lid margin telangiectases, and gland orifice plugging.
- Participants completed questionnaires and underwent slit-lamp examinations.
Main Results:
- The prevalence of symptomatic MGD was 11.2%, and total MGD (including asymptomatic) was 74.5%.
- MGD prevalence significantly increased with age (P < 0.0001).
- Patients with MGD showed more frequent slit-lamp findings, higher fluorescein scores, shorter tear film breakup times, and larger meibo-scores.
Conclusions:
- The prevalence of MGD in Tokyo is higher than in the Spanish population based on the applied diagnostic criteria.
- Age is a significant factor in MGD prevalence among the Japanese population studied.
