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Type 1 Gaucher disease (CYP2D6-eliglustat)

Laurent Becquemont1

  • 1Inserm, UMR 1184, CEA, DSV/iMETI, division of immuno-virology, IDMIT, pharmacology department, center for immunology of viral infections and autoimmune diseases, hôpital Bicêtre, Assistance publique-Hôpitaux de Paris, faculty of medicine Paris-Sud, university Paris-Sud, 78, rue du Général-Leclerc, 94275 Le Kremlin-Bicêtre, France.

Therapie
|March 1, 2017
PubMed
Summary

Eliglustat offers oral treatment for Type 1 Gaucher disease, but requires CYP2D6 genotyping. This genetic testing ensures correct dosing for ultra-rapid or slow metabolizers, optimizing treatment efficacy and safety.

Keywords:
EliglustatGaucher diseaseRare disease

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