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TorsinA regulates the LINC to moving nuclei
Daniel A Starr1, Lesilee S Rose1
1Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616 dastarr@ucdavis.edu lsrose@ucdavis.edu.
The Journal of Cell Biology
|March 1, 2017
Abstract:
How LINC complexes are regulated to connect nuclei to the cytoskeleton during nuclear migration is unknown. Saunders et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201507113) show that the AAA+ ATPase torsinA and its partner LAP1 are required for nuclear migration during fibroblast polarization by mediating the dynamics of LINC complexes.

