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Related Concept Videos

Dementia01:30

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
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[Preventive strategies for dementia].

Patrick Müller1, Marlen Schmicker2, Notger G Müller2,3,4

  • 1AG Neuroprotektion, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Leipziger Str. 44/Haus 64, 39120, Magdeburg, Deutschland. patrick.mueller@dzne.de.

Zeitschrift Fur Gerontologie Und Geriatrie
|March 1, 2017
PubMed
Summary
This summary is machine-generated.

Preventing dementia is crucial due to rising prevalence and lack of cures. Lifestyle changes, particularly combining cognitive and physical activities like dance, show promise for brain health and successful aging.

Keywords:
AgingAlzheimer diseaseDancingNeuroplasticityPhysical exercise

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Area of Science:

  • Neuroscience
  • Gerontology
  • Public Health

Background:

  • Increasing dementia prevalence necessitates preventive strategies.
  • Lack of causal pharmacological therapies highlights the need for lifestyle interventions.
  • Promoting successful aging involves reducing risk factors and enhancing neuroplasticity.

Purpose of the Study:

  • To summarize current developments in dementia prevention through lifestyle modifications.
  • To focus on the impact of cognitive and physical activity on neuroprotection.
  • To explore combined activities, such as dance training, for dementia prevention.

Main Methods:

  • Review of current literature on lifestyle factors and dementia prevention.
  • Analysis of the effects of cognitive and physical activity on neuroprotection.
  • Examination of dance training as a combined cognitive-physical intervention.

Main Results:

  • Lifestyle modifications are gaining importance in dementia prevention.
  • Cognitive and physical activities positively impact neuroprotection and support successful aging.
  • Dance training emerges as a promising integrated approach.

Conclusions:

  • Preventive strategies focusing on lifestyle factors are essential for combating dementia.
  • Combining cognitive and physical activities, like dance, may offer significant neuroprotective benefits.
  • Further rigorous randomized clinical trials are required to validate these findings.