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EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.
, Jan Van Deun1, Pieter Mestdagh2
1Laboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Cancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium.
Extracellular vesicle (EV) research requires better transparency for experiment reproducibility. The EV-TRACK knowledgebase centralizes EV biology and methods to promote standardized experimental guidelines.
Area of Science:
- Extracellular Vesicle (EV) Biology
- Biotechnology
- Scientific Reporting
Background:
- The field of extracellular vesicle (EV) biology faces challenges in experiment interpretation and replication.
- Lack of standardized reporting hinders scientific progress and validation of findings.
Purpose of the Study:
- To introduce EV-TRACK, a crowdsourcing knowledgebase designed to centralize EV biology and methodology.
- To encourage the adoption of experimental guidelines by researchers, reviewers, editors, and funders.
Main Methods:
- Development of the EV-TRACK crowdsourcing knowledgebase (http://evtrack.org).
- Centralization of information on EV biology and experimental methodologies.
Main Results:
- The EV-TRACK platform provides a centralized resource for EV research.
- It aims to stimulate the implementation of standardized experimental practices.
Conclusions:
- Improved transparency and standardized reporting are crucial for advancing EV biology.
- EV-TRACK serves as a valuable tool to facilitate these improvements and enhance experimental reproducibility.
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