[Advances of Diagnostic Biomarkers on Acute Graft Versus Host Disease -Review]

Fei-Yan Wang1, Chun-Ji Gao1

  • 1Department of Hematology, Chinese PLA General Hospital, Medical College of Chinese PLA, Beijing 100853, China.

Acute graft-versus-host disease (aGVHD) is one of the main complications after allogeneic hematopoietic stem cell transplantation (HCT), resulting in considerable morbidity and mortality. Diagnosis of aGVHD is typically based on clinical presentation and confirmed by biopsy. In recent years, aGVHD researches have been focused on diagnostic biomarkers, and several microRNAs, cytokines and immunoregulated cells have been dicovered currently. This review summarizes the advances on aGVHD biomarkers.