Related Experiment Video
Updated: Mar 7, 2026

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
Published on: October 20, 2023
Management of Hypertension in Patients with Aortic Valvular Stenosis
Kanishk Agnihotri1, Vikas Singh2, Sidakpal S Panaich3
1Saint Peters University Hospital New Brunswick, NJ, United States.
Insights
Managing hypertension in aortic stenosis (AS) requires careful consideration of hemodynamic changes. This review examines antihypertensive agents for patients with AS, highlighting the need for further clinical trials.
Area of Science:
- Cardiology
- Hypertension Management
- Valvular Heart Disease
Background:
- Aortic stenosis (AS) prevalence increases with age and often coexists with hypertension.
- Hypertension is linked to higher mortality in patients with AS.
- Managing hypertension in AS is complex due to hemodynamic and structural heart changes.
Purpose of the Study:
- To review antihypertensive agents for managing hypertension in patients with aortic stenosis.
- To highlight the need for further randomized control trials in this specific patient population.
Main Methods:
- Literature review of existing studies and clinical guidelines.
- Analysis of antihypertensive strategies in the context of AS pathophysiology.
- Discussion of the impact of comorbidities on treatment decisions.
Main Results:
- Current management of hypertension in AS necessitates a cautious approach.
- Various antihypertensive agents may be considered, but specific evidence for AS populations is limited.
- Comorbidities significantly influence treatment choices.
Conclusions:
- Further randomized controlled trials are essential to guide antihypertensive therapy in AS patients.
- Tailored management strategies are crucial for patients with AS and hypertension.
- Understanding the interplay between AS, hypertension, and comorbidities is key for optimal patient outcomes.
Abstract:
Aortic stenosis (AS) has an increasing prevalence with age and is commonly associated with hypertension. While it has been established that hypertension is associated with increased mortality in patients with AS, further randomized control trials addressing the use of antihypertensives specifically in patients with AS are needed. The management of hypertension in patients with AS needs a cautious approach due to complex hemodynamic and structural changes involved. Comorbidities like coronary artery disease, heart failure and arrhythmias further dictate management of hypertension in patients with AS. The aim of this article is to review the various agents used in the management of hypertension in patients with AS.
More Related Videos
Related Concept Videos
Aortic Regurgitation III: Medical Management
Mitral Stenosis III: Medical Management
Hypertension V: Nursing Management
Aortic Regurgitation IV: Nursing Management
Mitral Stenosis IV: Nursing Management
Atherosclerosis III: Management

