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Un(MaSC)ing Stem Cell Dynamics in Mammary Branching Morphogenesis
Erin Greenwood1, Emma D Wrenn1, Kevin J Cheung1
1Translational Research Program, Public Health Sciences and Human Biology Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Developmental Cell
|March 2, 2017
Abstract:
The properties of stem cells that participate in mammary gland branching morphogenesis remain contested. Reporting in Nature, Scheele et al. (2017) establish a model for post-pubertal mammary branching morphogenesis in which position-dependent, lineage-restricted stem cells undergo cell mixing in order to contribute to long-term growth.

