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Related Concept Videos

Phases of Wound Repair01:28

Phases of Wound Repair

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Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
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Related Experiment Video

Updated: Mar 7, 2026

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
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A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

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New trends in posttraumatic soft tissue defect coverage.

A Berger1, R Hierner1

  • 1Klinik für Plastische, Hand- und Wiederherstellungschirurgie, Schwerverbrannten Zentrum, Medizinische Hochschule Hannover, Germany.

Der Orthopade
|March 2, 2017
PubMed
Summary
This summary is machine-generated.

Managing posttraumatic soft tissue defects requires understanding the defect, surgical timing, and treatment options. This study reviews extensive experience with various reconstructive techniques for optimal patient outcomes.

Keywords:
ClassificationKey words Soft tissue defectsTreatment

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Area of Science:

  • Reconstructive Surgery
  • Trauma Management
  • Tissue Engineering

Background:

  • Posttraumatic soft tissue defects, with or without fractures, pose significant diagnostic and treatment challenges.
  • Etiology and severity of defects vary, complicating treatment decisions.
  • Primary closure is not always feasible, necessitating advanced reconstructive strategies.

Purpose of the Study:

  • To present a comprehensive treatment concept for posttraumatic soft tissue defects.
  • To emphasize the importance of defect assessment, surgical timing, and knowledge of treatment options.
  • To integrate new therapeutic concepts with established methods.

Main Methods:

  • Review of personal experience from 1981-1995.
  • Analysis of over 5000 skin transplantations.
  • Evaluation of 3000 local tissue transfers, 200 distant flap transfers, and 1200 free microvascular tissue transfers.

Main Results:

  • Extensive experience with diverse reconstructive techniques has been accumulated.
  • A robust understanding of defect management has been developed.
  • The study highlights the successful application of various tissue transfer methods.

Conclusions:

  • Optimal therapy for posttraumatic soft tissue defects relies on thorough evaluation and knowledge of all available options.
  • Established reconstructive techniques remain valuable and are complemented by new therapeutic approaches.
  • Integrated treatment strategies ensure comprehensive management of complex soft tissue injuries.