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Apathy dimensions in Parkinson's disease.

Ratko Radakovic1,2,3,4,5, Richard Davenport2, John M Starr3,5

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International Journal of Geriatric Psychiatry
|March 2, 2017
PubMed
Summary

Parkinson's disease (PD) patients exhibit apathy, particularly in executive function and initiation, impacting daily living but not motor function. The Dimensional Apathy Scale (DAS) is a reliable tool for assessing this multidimensional symptom in PD.

Keywords:
Parkinson's diseaseactivities of daily livingapathydepressionmotor symptoms, non-motor symptoms

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Apathy is a significant and debilitating symptom in Parkinson's disease (PD).
  • The multidimensional nature of apathy in PD requires further investigation.
  • Understanding apathy's specific dimensions is crucial for effective management.

Purpose of the Study:

  • To evaluate the psychometric properties of the Dimensional Apathy Scale (DAS) in Parkinson's disease patients.
  • To explore the multidimensional apathy profile in individuals with PD.
  • To establish the validity and reliability of the DAS as an assessment tool for apathy in PD.

Main Methods:

  • A cohort of 34 PD patients and 34 healthy controls participated.
  • Informants/carers (30 for each group) also completed apathy assessments.
  • Participants completed the DAS, Apathy Evaluation Scale, and Geriatric Depression Scale Short Form.

Main Results:

  • PD patients self-reported significantly higher apathy in executive and initiation dimensions compared to controls.
  • Informant ratings indicated significantly higher executive apathy in PD patients versus controls.
  • Apathy dimensions were associated with impaired daily living activities but not motor disability.

Conclusions:

  • The Dimensional Apathy Scale (DAS) is a valid and reliable instrument for assessing multidimensional apathy in Parkinson's disease.
  • Parkinson's disease is characterized by an executive apathy profile, as perceived by caregivers, and also involves initiation apathy reported by patients.
  • These findings highlight a lack of motivation in planning, organization, attention, and initiation, warranting further research into cognitive underpinnings and clinical impact.