[Metagenomic analysis of samples in cystitis]

Detecting bacteria in pathological material and testing their sensitivity to antibiotics is essential in determining a treatment strategy and the choice of antimicrobial therapy. The results of the study showed that metagenomic analysis detects more bacteria in the pathological material than standard laboratory methods. We found a variety of bacteria, described as causative agents of urinary tract infections, evading the standard culture conditions used in routine diagnostic laboratories. These data show that in urinary tract infections mixed pathogens may be much more common than usually believed. At that, the pathological process involves bacteria with unexplored pathogenicity and sensitivity to antibiotics.