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Related Concept Videos

Pharmaceutical Equivalents01:26

Pharmaceutical Equivalents

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As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
235
Biopharmaceutical Factors Influencing Drug Product Design: Overview01:22

Biopharmaceutical Factors Influencing Drug Product Design: Overview

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Rational drug product design integrates knowledge of the drug’s physicochemical properties, formulation components, manufacturing techniques, and intended route of administration. Each factor influences the drug’s performance, including how it is released, absorbed, and eliminated in the body.The physicochemical properties of a drug—such as solubility, stability, and particle size—affect its compatibility with excipients and the choice of dosage form. Excipients, though...
389
Clinically Relevant Drug Product Specifications: Methods of Establishment01:29

Clinically Relevant Drug Product Specifications: Methods of Establishment

275
Product specifications define the acceptable quality of a pharmaceutical product by ensuring identity, purity, potency, and strength. These specifications serve as benchmarks during development, manufacturing, and post-approval quality control. Clinically relevant specifications are particularly important because they directly relate to a drug's safety and efficacy in clinical use.Dissolution studies are critical biopharmaceutic tools that link in vitro behavior to in vivo performance. They...
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Pharmaceutical Alternatives: Excipients and Impurities-Related Therapeutic Nonequivalence01:19

Pharmaceutical Alternatives: Excipients and Impurities-Related Therapeutic Nonequivalence

218
Pharmaceutical products contain more than just the active drug; they also contain various excipients such as binders, solubilizers, stabilizers, preservatives, and other elements. In some cases, impurities or contaminants might be present. Traditionally, quality control in pharmaceuticals has primarily focused on the analysis of the active drug, often overlooking the impact of these additional components. The recent issue with heparin contamination by over-sulfated chondroitin sulfate, a...
218
Drug Nomenclature01:17

Drug Nomenclature

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During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...
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Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence01:27

Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence

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Changes in polymorphic forms can significantly influence the bioavailability of poorly soluble drugs. Although the FDA defines pharmaceutical equivalence based on having the same active ingredient, dosage form, and route of administration, it does not automatically disqualify products with different polymorphic forms. This means two products with different polymorphs can still be deemed pharmaceutically equivalent. However, polymorphic differences can affect properties like wettability,...
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The big medication information dilemma.

Jane Bates1

  • 1Hampshire.

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|March 2, 2017
PubMed
Summary
This summary is machine-generated.

Patients often research drug side effects, but this can lead to anxiety. Understanding patient information-seeking behaviors is crucial for healthcare providers to offer appropriate support and guidance.

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Area of Science:

  • Nursing Ethics
  • Patient Education
  • Health Communication

Background:

  • Patients frequently seek information about their medications, including potential side effects.
  • The desire for information can stem from a proactive approach to health management.
  • However, excessive information seeking may lead to increased anxiety and distress.

Purpose of the Study:

  • To explore the phenomenon of patients researching drug side effects.
  • To understand the ethical considerations for nurses when patients engage in this behavior.
  • To provide insights into effective communication strategies for managing patient-driven information seeking.

Main Methods:

  • Qualitative study involving patient interviews and nursing focus groups.
  • Analysis of patient narratives regarding medication information seeking.
  • Ethical case study analysis within a nursing context.

Main Results:

  • Patients' information-seeking is often driven by a desire for control and understanding.
  • Nurses face ethical dilemmas in balancing patient autonomy with potential psychological harm from side effect information.
  • Effective communication and tailored information provision are key to mitigating patient anxiety.

Conclusions:

  • Healthcare providers should acknowledge and address patients' information-seeking behaviors.
  • Nurses require support and training to navigate the ethical complexities of discussing drug side effects.
  • Promoting shared decision-making and providing evidence-based information can empower patients while managing anxiety.