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Mechanisms of Immune Signaling in Colitis-Associated Cancer

Maximilian J Waldner1, Markus F Neurath1

  • 1Department of Medicine 1, University of Erlangen-Nuremberg, Erlangen, Germany.

Cellular and Molecular Gastroenterology and Hepatology
|March 2, 2017
PubMed

Keywords:
AOM-DSS, azoxymethane–dextran sulfate sodiumAPC, adenomatous polyposis coliCAC, colitis-associated cancerCD, Crohn’s diseaseCRC, colorectal cancerColorectal CancerCrohn's DiseaseCytokinesDDR, DNA damage responseIBD, inflammatory bowel diseaseIKK, IκB kinaseIL, interleukinIL6R, interleukin 6 receptorInflammatory Bowel DiseaseInterleukin-6LPS, lipopolysaccharideMyd88, myeloid differentiation primary response gene 88NF-κB, nuclear factor-κBNLR, NOD- and leucine-rich repeat–containing proteinNLRP, nucleotide-binding oligomerization domain- and leucine-rich repeat–containing protein family, pyrin domain-containingNOD, nucleotide-binding oligomerization domainRONS, reactive oxygen and nitrogen speciesSTAT3, signal transducer and activator of transcription 3TLR, Toll-like receptorTNF, tumor necrosis factorTNFR, tumor necrosis factor receptorTh17, T-helper 17Tumor Necrosis Factor AlphaUC, ulcerative colitisUlcerative Colitisgp, glycoprotein

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