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Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
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Post-approval, manufacturers may modify an approved new or generic drug product. Such modifications can encompass alterations in the Active Pharmaceutical Ingredient (API), manufacturing process, formulation, batch size, manufacturing site, and container closure system (FDA Guidance for Industry, April 2004). Often, a drug product may undergo multiple changes.These modifications require careful evaluation to determine their potential impact on the drug product's identity, strength, quality,...
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Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
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Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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Biologics, derived from living sources such as humans, animals, or microorganisms, represent a significant category of pharmaceuticals. These complex molecules, developed through advanced biotechnological methods or purified from natural sources, include essential medical treatments like insulin and growth hormones. The complexity of biologics arises from their large molecular structures and the intricate processes required for their production, making them distinct from conventional...
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Patent Highlights October-November 2016.

Hermann Am Mucke1

  • 1H.M. Pharma Consultancy, A-1160 Wien (Vienna), Austria.

Pharmaceutical Patent Analyst
|March 2, 2017
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Summary

Recent patent literature reveals key advancements in pharmaceutical and medical research. These innovations offer potential breakthroughs for future drug discovery and therapeutic development.

Area of Science:

  • Pharmaceutical Sciences
  • Medical Technology
  • Biotechnology

Background:

  • The patent landscape is a critical indicator of innovation.
  • Tracking patent filings provides insights into emerging trends and R&D focus areas.
  • Recent developments in pharmaceutical and medical fields necessitate a review of intellectual property.

Purpose of the Study:

  • To provide a concise overview of significant recent patents.
  • To highlight innovations relevant to pharmaceutical and medical research and development.
  • To identify emerging trends in drug discovery and medical device technology.

Main Methods:

  • Systematic review of recent patent filings.
  • Analysis of patents related to therapeutic agents and medical devices.

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  • Categorization of patents based on therapeutic area and technological innovation.

    • Main Results:

    • Identification of novel drug delivery systems.
    • Emerging patents in targeted cancer therapies.
    • Advancements in diagnostic tools and personalized medicine.

    Conclusions:

    • The patent literature reflects a dynamic R&D environment.
    • Key areas of innovation include novel therapeutics and advanced diagnostics.
    • Future pharmaceutical and medical development will likely be shaped by these patented technologies.