Related Experiment Video
Updated: Mar 7, 2026

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Mucous Membrane Pemphigoid Causing Central Airway Obstruction
Bilal A Jalil1, Yara G Abdou, Stephanie A Rosen
1*Department of Pulmonary, Critical Care & Sleep Disorders Medicine, University of Louisville, Louisville, KY Departments of †Internal Medicine §Pulmonary and Critical Care Medicine, University of New Mexico, Albuquerque ‡CHRISTUS St. Vincent Regional Medical Center, Santa Fe, NM.
Mucous membrane pemphigoid (MMP) is a rare autoimmune disease causing airway obstruction. Successful treatment involved bronchoscopic resection and mycophenolate, leading to remission.
Area of Science:
- Autoimmune diseases
- Pulmonology
- Dermatology
Background:
- Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease primarily affecting mucous membranes.
- MMP infrequently involves the respiratory tract, characterized by subepithelial blister formation and potential scarring.
- Immunopathology shows immunoglobulin and complement deposition in the subepithelial basement membrane.
Related Concept Videos
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Chronic Obstructive Pulmonary Disease-V: Nursing Management
Assessment

